毛囊相关干细胞及毛囊再生研究进展
首发时间:2022-04-13
摘要:毛囊(HF)是一种微小的皮肤附属物,具有周期性的再生能力,但是多种原因会导致毛囊功能丧失,造成脱发。当前,构建功能性的毛囊仍然是一个巨大的挑战,根据谱系追踪技术和对毛囊细胞群的基因表达分析增强了我们对于毛发再生机制的理解,为构建功能性的毛囊奠定了理论基础。基于此,本文总结了当前用于毛囊再生的各类种子细胞,简明阐述了恢复毛囊功能的研究方法和策略,最后总结了毛囊再生领域当前的研究现状,并对该领域的未来趋势进行了展望。
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Research progress in the study of hair follicle-associated stem cells and hair follcile regeneration
Abstract:Hair follicles (HF) are tiny skin appendages with the ability to regenerate periodically, but a variety of etiologies can lead to loss of follicular functions. It is still challenging to construct functional hair follicles, but gene expression analysis based on gene tracing techniques and follicular cell populations has strongly increased our understanding of the mechanisms of hair regeneration. Here we summarise different seed cells for hair follicle regeneration, provide a concise but comprehensive overview of research methods and strategies for restoring hair follicle functions, and conclude with a summary of current research advances and future trends in the field of hair follicle regeneration.
Keywords: Hair follicle regeneration review
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毛囊相关干细胞及毛囊再生研究进展
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