基于深度学习的冠状动脉钙化积分量化研究
首发时间:2022-03-18
摘要:冠心病严重威胁着我国人民的生命健康,在其病理特征中,冠状动脉钙化的特异性最高,且冠状动脉钙化积分能够较为准确地将心脏风险进行分层。本文提出了一种基于深度学习的冠状动脉钙化积分量化方法。首先,针对学界暂无公开数据集的情况,构建了一套基于冠状动脉造影图像的钙化数据集创建流程,包括其定义、生成步骤和规范。其次,针对冠状动脉钙化积分量化任务,提出了一个基于空间金字塔池化的残差网络,通过引入空间金字塔池化层,解决了多尺寸输入的问题,并在网络中融合全局上下文信息。在训练方式上,本文采用了多任务多分类的训练方法,提升了模型对钙化斑块的敏感度。最后,本文引入多种医学一致性检验方法检验了上述方法的可行性。
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Quantification of Coronary Artery Calcificatiion Scores Based on Deep Learning
Abstract:Coronary Heart Disease, abbreviated as CHD, is a serious threat to our citizens\' healthy and life.Coronary artery calcification, abbreviated as CAC, is the most specific pathological feature of CHD. Therefore, automated scoring of coronary artery calcification can improve the prediction of cardiovascular risk events.In this paper, we propose a quantification method of coronary artery calcification scores based on deep learning. Firstly, aiming at the lack of public datasets in the academic community, the paper constructs a process and specification for creating a calcification dataset based on coronary angiography images. Secondly, aiming at the task of coronary angiography calcification scoring, the paper proposes ReSPPNet, a residual network based on spatial pyramid pooling with optimized training method. The problem of multi-size input is solved by introducing a spatial pyramid pooling layer, while being able to fuse global information. Lastly, the feasibility of the above prediction methods was demonstrated using a medical consistency test.
Keywords: deep learning coronary angiography calcification score consistency checking
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