Roles of ubiquitin-26S proteasome system in plant disease development and resistance

• 1、College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058

Abstract：Ubiquitylation is one of the most important post-translational modification. Ubiquitylated proteins are often degraded by 26S proteasome. Ubiquitin-26S proteasome system conservatively exists in eukaryotes. Components of ubiquitin-26S proteasome system frequently account for high proportion of the whole genome. Ubiquitin-26S proteasome system is the major pathway to degrade proteins in higher plants. It is involved in the whole life processes of organisms, including cell cycle control, programmed cell death, plant development, self-incompatibility and signal transduction of light, sugar and hormones, and thus plays important roles in adaptation to environmental changes. In addition, more and more recent studies reveal that the ubiquitin-26S proteasome system is also essential to regulating plant disease development, defense responses and disease resistance. This paper reviews the progress on the composition, function and mechanisms of the ubiquitin-26S proteasome system in plant and its roles in plant defense responses and resistance as well as plant disease development.

Keywords： Plant pathology Ubiquitylation 26S proteasome Protein degradation Disease Resistance